Synthetic Route of 32005-36-0, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 32005-36-0, Name is Bis(dibenzylideneacetone)palladium, molecular formula is C34H28O2Pd. In a Article£¬once mentioned of 32005-36-0
Access to beta-lactams by enantioselective palladium(0)-catalyzed C(sp3)-H alkylation
beta-Lactams are very important structural motifs because of their broad biological activities as well as their propensity to engage in ring-opening reactions. Transition-metal-catalyzed C-H functionalizations have emerged as strategy enabling yet uncommon highly efficient disconnections. In contrast to the significant progress of Pd0-catalyzed C-H functionalization for aryl-aryl couplings, related reactions involving the formation of saturated C(sp3)-C(sp3) bonds are elusive. Reported here is an asymmetric C-H functionalization approach to beta-lactams using readily accessible chloroacetamide substrates. Important aspects of this transformation are challenging C(sp3)-C(sp3) and strain-building reductive eliminations to for the four-membered ring. In general, the beta-lactams are formed in excellent yields and enantioselectivities using a bulky taddol phosphoramidite ligand in combination with adamantyl carboxylic acid as cocatalyst.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Synthetic Route of 32005-36-0. In my other articles, you can also check out more blogs about 32005-36-0
Reference£º
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method