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Tetradentate Platinum And Palladium Complex Emitters Containing Phenyl-Pyrazole And Its Analogues

A phosphorescent emitter or delayed fluorescent and phosphorescent emitters represented by Formula 1 or Formula II, where M is platiunum or palladium.

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Reference£º
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method

Final Thoughts on Chemistry for Pd2(DBA)3

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TETRAHYDROQUINOLINE DERIVATIVES USEFUL AS BROMODOMAIN INHIBITORS

Tetrahydroquinoline compounds pharmaceutical compositions containing such compounds and their use in therapy.

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Reference£º
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method

Final Thoughts on Chemistry for 52409-22-0

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2-(3-PHENYL-2-PIPERAZINYL-3,4-DIHYDROQUINAZOLINE-4-YL) ACETIC ACIDS AS ANTI-VIRAL AGENTS, ESPECIALLY AGAINST CYTOMEGALO VIRUSES

The invention relates to dihydroquinazolines and methods for the production thereof, the use thereof in the treatment and/or prophylaxis of diseases, in addition to the use thereof in the production of medicaments in the treatment and/or prophylaxis of diseases, especially for use as anti-viral agents, especially against cytomegalo viruses.

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Reference£º
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method

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In situ generation of phosphoryl alkylindiums and their synthetic application to arylalkyl phosphonates via palladium-catalyzed cross-coupling reactions

Phosphoryl alkylindium reagents are generated in situ from the direct insertion of indium with bromoalkyl phosphonates in the presence of CuCl, and their synthetic application to arylalkyl phosphonates is reported via a Pd-catalyzed cross-coupling reaction with tolerance of a diversity of functional groups including ester, ketone, aldehyde, nitrile, nitro, trifluoromethyl, chloride, methoxy, hydroxy, and amino.

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Reference£º
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method

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Tuning the electronic properties of porphyrin dyes: Effects of meso substitution on their optical and electrochemical behaviour

Two series of unsymetrically functionalized, carboxyethynylphenyl- containing porphyrins, bearing either 2,4,6-triisopropylphenyl or triphenylamino substituents at three of the four meso positions, have been prepared by Sonogashira coupling from the corresponding ethynyl- or iodo-functionalized porphyrin precursors. UV/Vis and electrochemical measurements have been performed to determine the electronic features of these new compounds and, hence, their potential as dyes for dye-sensitized solar cells. Copyright

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Reference£º
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method

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Fused bicyclic aromatic compounds that are useful in treating sexual dysfunction

The present invention relates to the use of compounds of formula (I) 1for the treatment of sexual dysfunction and to compositions containing compounds of formula (I) for the treatment of sexual dysfunction.

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Reference£º
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method

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Phosphine Control of the Oxidative Addition Chemistry of Tetrathiocins to Palladium(0): Characterization of Mono-, Di-, and Hexanuclear Palladium(II) Dithiolate Complexes

The outcome of the oxidative addition reactions of bis(4?,5?-dimethoxybenzo)-1,2,5,6-tetrathiocin to Pd2dba3 under microwave conditions is sensitive to the nature of the phosphine coreagent; the bidentate phosphines dppm, dppe, and dppf afford the mononuclear dithiolates (dmobdt)Pd(dppm) (4), (dmobdt)Pd(dppe) (2), and (dmobdt)Pd(dppf) (5), whereas more labile monodentate phosphines lead to aggregation; Ph3P afforded the dinuclear dithiolate (dmobdt)2Pd2(PPh3)2 (6), whereas tBu3P generated the phosphine-free hexanuclear edge-capped octahedral complex Pd6(dmobdt)6 (7) [dmobdt = 4,5-dimethoxybenzenedithiolate, (MeO)2C6H2S22-].

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Reference£º
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method

A new application about Pd2(DBA)3

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Methoxymethyl Threofuranosyl Thymidine (4?-MOM-TNA-T) at the T7 Position of the Thrombin-Binding Aptamer Boosts Anticoagulation Activity, Thermal Stability, and Nuclease Resistance

The synthesis of 4?-methoxymethyl threofuranosyl (4?-MOM-TNA) thymidine and derived oligomers of the G-rich thrombin-binding aptameric (TBA) sequence is reported. The G-quadruplex stability, anticoagulation activity, and the enzymatic stability of these oligomers bearing the 2?-3?-phosphodiester backbone as single substitutions in the loop regions are studied. Amongst all the oligomers, TBA-7T bearing the 4?-MOM-TNA unit at the T7 position formed a quadruplex with the highest thermal stability. It also resulted in enhanced anticlotting activity that allowed a one-third reduction in the dose, relative to TBA. Further, TBA-7T exhibited enhanced nuclease resistance properties to both endo- A nd exonucleases.

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Reference£º
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method

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Synthesis and characterization of the fluorinated thieno[3,4-c]pyrrole-4,6-dione-based donor-acceptor polymers for organic solar cells

A new wide bandgap polymer (PC8TPD-F) has been synthesized via the Stille cross-coupling reaction between fluorine-substituted thieno[3,4-c]pyrrole-4,6-dione (TPD) and 4,8-bis(5-hexylthiophen-2-yl)benzo[1,2-b:4,5-b]dithiophene (BDTT). For structural comparison, the nonfluorinated TPD-based BDTT polymer (PC8TPD) was also synthesized with the same polymerization. The number average molecular weights (Mn) of PC8TPD and PC8TPD-F were found to be 47,000 g/mol (? = 2.1) and 52,000 g/mol (? = 1.8) respectively. The HOMO levels of PC8TPD and PC8TPD-F were determined to be ?5.56 and?5.65 eV respectively. The inclusion of the fluorinated TPD unit lowers the polymer’s HOMO level. The SCLC mobilities of PC8TPD and PC8TPD-F were determined to be 1.5 ¡Á 10?4 and 2.1 ¡Á 10?4 cm2/V respectively. Polymer solar cell devices prepared with PC8TPD and PC8TPD-F as their active layers were found to exhibit power conversion efficiencies of 4.26% and 6.80% with open circuit voltages of 0.90 V and 0.95 V respectively.

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Reference£º
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method

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TRI-AND BI-CYCLIC HETEROARYL HISTAMINE-3 RECEPTOR LIGANDS

Compounds of formula (I) wherein R1 or R2 is a tricyclic or bicyclic ring, each of which contains at least two heteroatoms, and R1, R2, R3, R3a, R3b, R4, R5, L, X, X’, Y, Y’, Z, and Z’ are as defined herein, are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Also disclosed are pharmaceutical compositions comprising the histamine-3 receptor ligands, methods for using such compounds and compositions, and a process for preparing compounds within the scope of formula (I).

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Reference£º
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method