Category: 14871-92-2

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.14871-92-2,(2,2¡ä-Bipyridine)dichloropalladium(II),as a common compound, the synthetic route is as follows.

To a vigorously stirred solution of BzpheH2 (32.32 mg,0.12 mmol) in 8 mL CH3OH/H2O (V:V D 1:1), [Pd(bipy)Cl2] (20 mg, 0.06 mmol) was added. The mixture was heatedto 50C and adjusted to pH D 8-9 by NaOH solution, andthen stirred for 2 h. The solution was concentrated to about80% of the original volume. The complex I-a was separatedfrom the solution after a few days. Yellow crystalline, yield: 68%. IR (KBr, cm1): n(Amide&)1551, n(OCO)a 1632, n(OCO)a1383, n(Pd-N) 566, n(Pd-O) 465. 1H NMR (600 MHz, d6-DMSO) d (ppm): 3.08 (dd, J D 13.1, 4.5 Hz, 1H, CH2-H),3.29 (dd, J D 13.1, 4.5 Hz, 1H, CH2-H), 5.08-5.05 (m, 1H,CH), 6.65 (t, J D 7.5 Hz, 1H, Ar-H), 6.73 (t, J D 7.5 Hz, 2H,Ar-H), 7.09 (d, J D 3.0 Hz, 3H, Ar-H), 7.13 (d, J D 5.4 Hz,1H, Ar-H), 7.23 (d, J D 7.2 Hz, 2H, Ar-H), 7.28 (d, J D5.4 Hz, 1H, Ar-H), 7.78-7.75 (m, 1H, Ar-H), 8.02 (t, J D7.8 Hz, 1H, Ar-H), 8.26 (d, J D 7.8 Hz, 1H, Ar-H), 8.30 (t, JD 6.9 Hz, 4H, Ar-H), 8.42 (d, J D 7.8 Hz, 1H, Ar-H). ESIMS:568.03 [MCK]C. Anal. Calcd. for [Pd(bipy)(Bzphe-N,O)] (C26H21N3O3Pd, 529.06): C, 58.93; H, 3.99; N, 7.93.Found: C, 58.84; H, 4.04; N, 7.84.

14871-92-2 (2,2¡ä-Bipyridine)dichloropalladium(II) 6096670, acatalyst-palladium compound, is more and more widely used in various.

Reference£º
Article; Wang, Li-Wei; Liu, Si-Yuan; Wang, Jin-Jie; Peng, Wen; Li, Sheng-Hui; Zhou, Guo-Qiang; Qin, Xin-Ying; Wang, Shu-Xiang; Zhang, Jin-Chao; Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry; vol. 45; 7; (2015); p. 1049 – 1056;,
Chapter 1 An introduction to palladium catalysis
Palladium/carbon catalyst regeneration and mechanical application method

14871-92-2, (2,2¡ä-Bipyridine)dichloropalladium(II) is a catalyst-palladium compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: Palladium(II) chloride (PdCl2), 2,2?-bipyridine (bipy), 1,10-phenanthroline (phen), thiourea (TU, 1), N-methylthiourea (meTU, 2), N-buthylthiourea (buTU, 3), N,N?-diethylthiourea (dietTU, 4) and N,N?-dibuthylthiourea (dibuTU, 5) were purchased as pure reagents at AG, from Sigma Aldrich. Potassium tetrachloropalladate(II) was prepared by the reaction of palladium chloride with a slight excess of potassium chloride. The complexes [Pd(bipy)Cl2] and [Pd(phen)Cl2], were obtained by adding 1 mmol of the respective ligand to 0.326 g (1 mmol) of K2[PdCl4] suspended/dissolved in 40 mL of wet methanol under reflux for about 1 h. The precipitated crystalline powders were recovered by filtration and dried under vacuum for 2 h. 0.25 mmol of these complexes (83 and 89 mg, respectively) were then suspended again in a water/methanol mixture, whereupon 0.5 mmol of the respective thiourea (1-5) was added under reflux. After 1 h, clear yellow to orange solutions were obtained. These solutions were filtrated and the filtrates were kept for 3-5 days at room temperature for crystallization. As a result yellow-red crystals were obtained. The experimental yield of the products, based on Pd, was more than 50%. All the solvents, of analytical grade, were dried and deoxygenated before being used. Elemental analyses were performed at the Microanalytical Laboratory of Redox snc (Milano). Characterization details are extensively quoted in the supplementary material.

14871-92-2 (2,2¡ä-Bipyridine)dichloropalladium(II) 6096670, acatalyst-palladium compound, is more and more widely used in various.

Reference£º
Article; Rotondo, Archimede; Barresi, Salvatore; Cusumano, Matteo; Rotondo, Enrico; Polyhedron; vol. 45; 1; (2012); p. 23 – 29;,
Chapter 1 An introduction to palladium catalysis
Palladium/carbon catalyst regeneration and mechanical application method

14871-92-2, (2,2¡ä-Bipyridine)dichloropalladium(II) is a catalyst-palladium compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a yellow suspension containing 0.20 g (0.60 mmol) of [Pd(bpy)Cl2] in water (20 mL)was added 0.08 g (0.60 mmol) of HaptHCl. After the mixture was stirred at 50 C for 7 h, theresulting yellow solution was filtered. To the yellow filtrate was added an aqueous solution ofNaClO4 (2 M, 10 mL), followed by standing at room temperature for 1 d. The resulting yellowcrystals of [1](ClO4)4 suitable for X-ray analysis were collected by filtration. Yield: 0.32 g (87%).

The synthetic route of 14871-92-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Kouno, Masahiro; Miyashita, Yoshitaro; Yoshinari, Nobuto; Konno, Takumi; Chemistry Letters; vol. 44; 11; (2015); p. 1512 – 1514;,
Chapter 1 An introduction to palladium catalysis
Palladium/carbon catalyst regeneration and mechanical application method

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.14871-92-2,(2,2¡ä-Bipyridine)dichloropalladium(II),as a common compound, the synthetic route is as follows.

The new bimetallic dinuclear complex, [{PdCl(bipy)}{l-(NH2(CH2)6H2N)}{PtCl(bipy)}]Cl(ClO4), was synthesized by modificationof the procedure reported in the literature [25]. The complex[PtCl2(bipy)] (100.0 mg, 0.236 mmol) was dissolved in DMF(10 cm3) and a solution of AgClO4 (49.1 mg, 0.236 mmol) in DMF(5 cm3) was added. The mixture was stirred overnight in the dark,at room temperature. The precipitate AgCl was removed by filtrationand the resulting pale yellow solution of [PtCl(bipy)(DMF)]ClO4 was kept in a refrigerator to cool down. A suspension of[PdCl2(bipy)] complex (73.5 mg, 0.220 mmol) in 10 cm3 of DMFwas heated with stirring at 303-313 K for about 30 min. After that,the solution of 1,6-diaminohexane (25.5 mg, 0.220 mmol) in 5 cm3DMF was added dropwise. The mixture was stirred at room temperaturefor 5 h in the dark. The filtrate [PtCl(bipy)(DMF)]ClO4was added to the resulting mixture. The clear yellow solutionwas stirred for 3 h at 323 K and then for 24 h at room temperature.The solution was then evaporated and the residue washed withether. A light yellow powder was obtained and left to dry in theair. Yield (63.8 mg, 62%). Anal. Calc. for PtPdCl4O4N6C26H32(FW = 935.88): C, 33.37; H, 3.45; N, 8.98. Found: C, 33.07; H,3.80; N, 8.73%. 1H NMR characterization (D2O, 200 MHz). 1H NMR(d, ppm): 1.35-1.50 (m, CH2 C3, C4), 1.60-1.80 (m, CH2 C2, C5),2.95-3.06 (m, CH2 C1, C6), 7.30-7.42 (d, CH H5/H50(1)), 7.45-7.60 (d, CH H5/H50(2)), 7.65-7.84 (m, CH H4/H40(1)), 8.05-8.15(m CH H4/H40(2)), 8.17-8.28 m, CH H3/H30(1)), 8.32-8.40 (m, CHH3/H30(2)), 8.42-8.48 (d CH H6/H60(1)), 8.50-8.58 (d CH H6/H60(2)). IR (KBr, 4000-300 cm1): 3438 (N-H stretch); 2853, 2927(CH2 stretch); 1610 (CN stretch); 1089 (perchlorate counterion); 765, 812 (N-H wagging) (Fig. S1).

As the paragraph descriping shows that 14871-92-2 is playing an increasingly important role.

Reference£º
Article; Jovanovi?, Sne?ana; Petrovi?, Biljana; Petkovi?, Marijana; Bugar?i?, ?ivadin D.; Polyhedron; vol. 101; (2015); p. 206 – 214;,
Chapter 1 An introduction to palladium catalysis
Palladium/carbon catalyst regeneration and mechanical application method

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.14871-92-2,(2,2¡ä-Bipyridine)dichloropalladium(II),as a common compound, the synthetic route is as follows.

General procedure: To a stirred suspension of [Pd(bpy)Cl2] (0.03 g, 0.1 mmol) or[Pd(phen)Cl2] (0.04 g, 0.1 mmol) in MeOH (10 mL) a solution ofHhmbt (0.023 g, 0.1 mmol) in MeOH containing KOH (0.006 g,0.1 mmol; 10 mL) was added drop by drop with stirring. The reactionmixture was warmed for 48 h, upon which a yellow-orangeprecipitate was filtered off, washed with MeOH, Et2O and driedin vacuo.For[Pd(bpy)(hmbt)]Cl2H2O: Yield: 0.07 g (51%). ElementalAnal.: Calcd. C, 49.5; H, 4.3; N, 12.6; Pd, 19.1 (C23H24N5O3Pd);Found: C, 49.7; H, 4.2; N, 12.7; Pd, 19.1%. Conductivity data(103 M in DMF): KM = 84.0 ohm1. IR (cm1): m(CN), 1621;m(CO), 1251; m(N-N), 1141; m(Pd-O), 500; m(Pd-N), 459. Raman(cm1): m(CN), 1602; m(CO), 1251; m(N-N), 1141; m(Pd-O), 501;m(Pd-N), 460. 1H NMR (ppm): 8.00 (H(3), d, J = 6 Hz, 1H); 7.75(H(6), S, 1H); 7.86 (H(7), d, J = 5.4 Hz, 1H); 7.73 (H(8), t, J = 5 Hz,1H); 7.69 (H(9), t, J = 5 Hz, 1H); 7.22 (H(10), d, J = 5.2 Hz, 1H);2.50 (CH3, S, 3H). MS (m/z): 486.4 (Calcd. 486.4), 368.2 (Calcd.368.4), 292.4 (Calcd. 292.4), 262.4 (Calcd. 262.4), 156.3 (Calcd.156.0).For[Pd(phen)(hmbt)]ClH2O: Yield: 0.08 g (54%). ElementalAnal.: Calcd. C, 53.2; H, 3.9; N, 12.4; Pd, 18.7 (C25H22N5O2Pd);Found: C, 53.3; H, 4.0; N, 12.3; Pd, 18.6%. Conductivity data(103 M in DMF): KM = 81.0 ohm1. IR (cm1): m(CN), 1600;m(CO), 1252; m(N-N), 1138; m(Pd-O), 564; m(Pd-N), 495. Raman(cm1): m(CN), 1604; m(CO), 1252; m(N-N), 1139; m(Pd-O), 565;m(Pd-N), 495. 1H NMR (ppm): 7.96 (H(3), d, J = 5.1 Hz, 1H); 7.30(H(6), S, 1H); 7.60 (H(7), d, J = 4.5 Hz, 1H); 7.77 (H(8), t,J = 4.2 Hz, 1H); 7.73 (H(9), t, J = 4.5 Hz, 1H); 7.22 (H(10), d,J = 4.2 Hz, 1H); 2.50 (CH3, S, 3H). MS (m/z): 510.4 (Calcd. 510.4),286.4 (Calcd. 286.4), 180.6 (Calcd. 180.0).

As the paragraph descriping shows that 14871-92-2 is playing an increasingly important role.

Reference£º
Article; El-Asmy, Hala A.; Butler, Ian S.; Mouhri, Zhor S.; Jean-Claude, Bertrand J.; Emmam, Mohamed S.; Mostafa, Sahar I.; Journal of Molecular Structure; vol. 1059; 1; (2014); p. 193 – 201;,
Chapter 1 An introduction to palladium catalysis
Palladium/carbon catalyst regeneration and mechanical application method

14871-92-2, (2,2¡ä-Bipyridine)dichloropalladium(II) is a catalyst-palladium compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Mefenamic acid (0.40 mmol) was dissolved in methanol (15 mL) followed by the addition of KOH (0.40 mmol). After 60 min of stirring, the resulting solution was slowly added to an aqueous solution of [PdCl2(bipy)] (0.20 mmol). After 40 min of constant stirring, the yellow solid obtained was collected by filtration, washed with ethanol and dried in a desiccator with P4O10. The yield was 63%. Anal. Calc. for [Pd(C15H14NO2)2(bipy)] (%): C 64.6; H 4.88;N 7.54. Found: C 63.3; H 4.74; N 7.62. The complex is soluble inchloroform and insoluble in water and DMSO. As already observed for the Pd-tra complex, no single crystals were obtained to perform an X ray structural characterization. The [PdCl2(bipy)] complexused as a precursor in the synthesis of Pd-mef was synthesized as described in the literature [21].

14871-92-2 (2,2¡ä-Bipyridine)dichloropalladium(II) 6096670, acatalyst-palladium compound, is more and more widely used in various.

Reference£º
Article; Carvalho, Marcos A.; Arruda, Eduardo G.R.; Profirio, Daniel M.; Gomes, Alexandre F.; Gozzo, Fabio C.; Formiga, Andre L.B.; Corbi, Pedro P.; Journal of Molecular Structure; vol. 1100; (2015); p. 6 – 13;,
Chapter 1 An introduction to palladium catalysis
Palladium/carbon catalyst regeneration and mechanical application method

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.14871-92-2,(2,2¡ä-Bipyridine)dichloropalladium(II),as a common compound, the synthetic route is as follows.

Direct synthesis from 1a, CF3SO3Ag, and [Pd(bipy)Cl2]. A solution of Pd(bipy)Cl2 (0.10 g, 0.30 mmol) in 5 mL of CH3CN and a solution of CF3SO3Ag (0.15 g, 0.58 mmol) in 5 mL of CH3CN were mixed and heated under reflux for a day. Precipitates were filtered off and the solvent was evaporated. The resultant pale yellow powder was dissolved in a mixture of CH3CN and CHCl3, and then 1a (0.35 g, 0.58 mmol) was added. The mixture was heated under reflux for a day, and then, filtered and the solvents were removed under reduced pressure. Resultant material was recrystallized from CH3CN- CHCl3 mixture twice. White fibers (0.27 g, 46.0%) were obtained. Mp. 249-252 C (dec.). 1H NMR ( CDCl3/CD3CN = 4/1, v/v, 300 MHz): delta 10.41 (brs, 8H, OH), 9.35 (brs, 4H, Py-H), 8.33 (d, J = 7.5 Hz, 2H, bipy-H), 8.26 (t, J = 7.0 Hz, 2H, bipy-H), 7.92 (brs, 4H, Py-H), 7.51 (t, 2H, bipy-H), 7.26 (d, J = 4.4 Hz, 2H, bipy- H), 6.99 (s, 4H, ArH), 6.95 (s, 4H, ArH), 6.89 (s, 4H, ArH), 6.67 (s, 4H, ArH), 4.11 (d, J = 13.8 Hz, 2H. CH2), 4.02 (d, J = 13.6 Hz, 4H. CH2), 3.80 (brs, 4H, CH2), 3.66 (brd, J = 10.8 Hz, 4H, CH2), 3.47 (brd, J = 13.8 Hz, 4H. CH2), 3.43 (brd, J = 12.9 Hz, 2H. CH2), 3.32 (d, J = 12.9 Hz, 4H, CH2), 2.19, 2.17 (s, 24H, CH3). 13C NMR ( CDCl3/CD3CN = 4/1, v/v, 75.6 MHz): delta 157.0, 153.2, 151.7, 150.7, 149.7, 147.2, 142.3, 131.2, 131.1, 130.0, 129.6, 129.5, 128.2, 128.0, 127.8, 127.8, 127.7, 124.2, 123.0, 121.0, 118.8, 57.7, 56.7, 32.0, 31.5, 20.5, 20.3. FABMS: m/z: 1611.5 ( M+); HRMS (FAB): calcd for C89H88F3N6O11S106Pd ( M2+ + TflO-), 1611.5219. Found: 1611.5231.

As the paragraph descriping shows that 14871-92-2 is playing an increasingly important role.

Reference£º
Article; Takemura, Hiroyuki; Mogami, Yukako; Okayama, Kanae; Nagashima, Noriko; Orioka, Kana; Hayano, Yuri; Kobayashi, Asako; Iwanaga, Tetsuo; Sako, Katsuya; Journal of Inclusion Phenomena and Macrocyclic Chemistry; vol. 95; 3-4; (2019); p. 235 – 246;,
Chapter 1 An introduction to palladium catalysis
Palladium/carbon catalyst regeneration and mechanical application method

14871-92-2, (2,2¡ä-Bipyridine)dichloropalladium(II) is a catalyst-palladium compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

[Pd(bpy)Cl2] (.67 g, 2 mmol) was suspended in 200 mlacetone-water (3:1 v/v) and AgNO3 (.68 g, 4 mmol) wasadded with constant stirring. This mixture was heated at328 K with stirring in the dark for 6 h followed by stirringfor 16 h at room temperature. The AgCl precipitatewas removed by filtration using Whatman 42 filter paper.The clear yellow filtrate was mixed with mu-paraxylidinebisdithiocarbamatedisodium salt (.33 g, 1 mmol).The reaction mixture was subsequently stirred for 5 h at318 K and then filtered. The clear solution was concentratedto 5 ml at 318 K. The resulting yellow precipitatewas filtered and washed with small amounts of acetoneand resolved in 300 ml doubly distilled water at 318 K.The solution was filtered to remove turbidity. The clearsolution was then concentrated to 5 ml and refrigeratedovernight. The yellow precipitate was filtered and washedwith small amounts of cold distilled water and acetoneand dried in an oven at 318 K. The synthesis of the complexcan be summarized by Figure 1. Yield: .572 g(65%), Decomposition ranges: 520-523 K. Anal. Calcd.for C30H26N6S4Cl2Pd2: C, 40.86; H, 2.95, N, 9.53%.Found: C, 40.85; H, 2.96, N, 9.55%. Molar conductance,LambdaM (H2O, Omega-1 mol-1 cm2): 243. FT-IR (KBr pellets,cm-1): 1541 upsilon (C-N); 1022 upsilon (C-S) and 1385 (NO3- ion).UV-Vis data (water, lambdamax/nm (logepsilon): 308 (3.43), 247 (3.79) and 188 (3.95). 1H NMR (500 MHz, DMSO-d6,ppm, d = doublet, t = triplet and m = multiple): 7.66 (m,1H, H-a), 8.23 (m, 2H, H-b), 8.48 (d, 2H, H-c), 7.79(t, 2H, H-5,5), 8.30 (t, 2H, H-4,4), 8.57 (d, 2H, H-3,3),8.88 (d, 2H, H-6,6) (Figure S1).

14871-92-2 (2,2¡ä-Bipyridine)dichloropalladium(II) 6096670, acatalyst-palladium compound, is more and more widely used in various.

Reference£º
Letter; Saeidifar, Maryam; Sohrabi Jam, Zahra; Shahraki, Somayeh; Khanlarkhani, Ali; Javaheri, Masoumeh; Divsalar, Adeleh; Mansouri-Torshizi, Hassan; Akbar Saboury, Ali; Journal of Biomolecular Structure and Dynamics; vol. 35; 12; (2017); p. 2557 – 2564;,
Chapter 1 An introduction to palladium catalysis
Palladium/carbon catalyst regeneration and mechanical application method

With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.14871-92-2,(2,2¡ä-Bipyridine)dichloropalladium(II),as a common compound, the synthetic route is as follows.

10 mL ofa solution of AgNO3 (0.204 g, 1.2 mmol) was added to aqueous suspension of Pd(bipy)Cl2 (0.2 g, 0.6 mmol) acidified to pH 2-3. The formed suspension was homogenized and incubated during 1 h at 60C.

The synthetic route of 14871-92-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Nikandrov; Grigor’Eva; Eremin; Ruzanov; Gurzhii; Belyaev; Russian Journal of General Chemistry; vol. 85; 8; (2015); p. 1992 – 1993; Zh. Obshch. Khim.; vol. 85; 8; (2015); p. 1405 – 1406,2;,
Chapter 1 An introduction to palladium catalysis
Palladium/carbon catalyst regeneration and mechanical application method

14871-92-2, (2,2¡ä-Bipyridine)dichloropalladium(II) is a catalyst-palladium compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Synthesis of [Pd{OC(O)CH2N(COPh)}(bipy)] 2 A mixture of [PdCl2(bipy)] (210 mg, 0.63 mmol) with hippuric acid (113 mg, 0.63 mmol) and silver(I) oxide (600 mg) in dichloromethane (30 mL) was refluxed for 3.5 h. Methanol (30 mL) was added, and the mixture filtered to give a clear yellow solution. The solid residue was extracted with an additional 40 mL of dichloromethane-methanol (1:1 v/v), and the filtrates combined. The solution was evaporated to dryness, redissolved in dichloromethane (40 mL) and the product precipitated by addition of petroleum spirits (40 mL). The solid was filtered, washed with petroleum spirits (10 mL) and dried under vacuum to give 2 as an orange solid (192 mg, 69%). Found: C 50.2; H 3.45; N 9.1. C18H15N3O3Pd requires C 50.5; H 3.5; N 9.8%. (0043) 1H NMR, delta 9.12-6.91 (m, bipy and Ph), 4.26 (s, CH2). ESI MS (added NaHCO2, capillary exit voltage 140 V): [M+Na]+ m/z 461.88 (100%), calculated for C19H15N3O3PdNa m/z 462.00.

The synthetic route of 14871-92-2 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Sim, Sophie A.; Saunders, Graham C.; Lane, Joseph R.; Henderson, William; Inorganica Chimica Acta; vol. 450; (2016); p. 285 – 292;,
Chapter 1 An introduction to palladium catalysis
Palladium/carbon catalyst regeneration and mechanical application method