Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. Application In Synthesis of Tris(dibenzylideneacetone)dipalladium-chloroform. Introducing a new discovery about 52522-40-4, Name is Tris(dibenzylideneacetone)dipalladium-chloroform
(-)-Ascochlorin was synthesized using palladium-catalyzed three component coupling reaction. Reaction of the aryl iodide 3, isoprene, and sodium p-toluenesulfinate in the presence of Pd2(dba)3CHCl 3 catalyst and NaHCO3 gave the 4-aryl-2-methyl-2- butenylsulfone 5 selectively in 68% yield. The allylic sulfone 5 was converted into the useful intermediate 2 in 5 steps, which was subjected to Julia olefination with the aldehyde 4 and deprotection gave (-)-ascochlorin. Copyright
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.Application In Synthesis of Tris(dibenzylideneacetone)dipalladium-chloroform, you can also check out more blogs about52522-40-4
Reference：
Chapter 1 An introduction to palladium catalysis,
Palladium/carbon catalyst regeneration and mechanical application method